Figure 6.

Cardiac function in wild-type and MyBP-C(Neo) mice. (a–c) Schematic and M-mode echocardiographic tracings from 12-week-old wild-type (b) and MyBP-C(Neo) mice (c). LV dimensions are calculated from measurements of anterior wall (1), posterior wall (2), end-diastolic diameter (3), and end-systolic diameter (4). Increased contrast in the posterior papillary muscle probably reflects calcification (c) (arrow). (d) Pressure volume relations and dP/dt profiles of wild-type (+/+) and MyBP-C(Neo) mice (t/t).