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. 1999 Nov 1;104(9):1223–1233. doi: 10.1172/JCI7458

Figure 4.

Figure 4

(a) In vitro perfusion pressures in superior mesenteric vasculature after inhibition of NO synthesis by incubation with L-NNA. *P < 0.05 vs. control. **P < 0.001 vs. control. Blockade of NO formation corrected the hyporesponsiveness to MTx that is related to the presence of BT in cirrhotic rats. (b) Dose-response curves for MTx in de-endothelialized superior mesenteric vascular beds. *P < 0.05 vs. LC, BT+ and LC, BT–. **P < 0.001 vs. LC, BT+ and LC, BT–. P < 0.001 for control vs. LC, BT+ and LC, BT– (ANOVA). Note the lack of difference in vascular reactivity in mesenteric preparations from cirrhotic rats with and without BT.