(a) Serum NOx concentrations. *P < 0.0001 vs. control. #P < 0.0001 vs. LC, BT–. (b) Serum NOx levels correlated significantly with TNF-α concentrations in MLNs (r = 0.561, P < 0.0001). (c) BH4 concentrations in mesenteric vasculature. *P < 0.05 vs. control. #P < 0.05 vs. LC, BT–. (d) Levels of BH4 in the studied vasculature were significantly correlated with TNF-α concentrations in MLNs (r = 0.524, P < 0.01), indicating an induction of BH4 synthesis by BT and an associated increase in TNF-α synthesis.