Figure 8.

IL-9R is found in the human airway. Bronchial biopsies were immunostained for the presence of IL-9R with DAB (brown) and counterstained with hematoxylin (purple). (a) A representative slide (×40 magnification) is shown; the receptor for IL-9 was found dispersed throughout the pseudostratified bronchial epithelium (e) and in the lamina propria associated with vascular endothelium (arrow). The basal lamina (BL) is also indicated for reference. (b) An Ig isotype control (anti-trinitrophenol) showed no DAB staining. (c) The IL-9 receptor was also shown by Western blot and immunostaining to be present on NCI-H292 cells in culture.