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Histology of the colon in mITF/DT-A transgenic mice (a and b) and in normal control mice (c and d) after oral 2.5% DSS administration. Both groups of mice were treated with 2.5% DSS in their drinking water for 12 days. Experimental colitis in normal mice caused by DSS was histologically more severe than in mITF/DT-A transgenic mice. (a and b) Hematoxylin and eosin staining. (c and d) AB-PAS staining. Epithelial restitution is more frequently seen in DT-A transgenic mice.
