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A single dose of mFlt(1–3)-IgG given 30 minutes before onset of ischemia affords a significant reduction in lesion volume. The lesion volume is defined as the region of single hyperintensity on the T2-weighted MRI recorded 1 day after 30 minutes of ischemia with reperfusion. Values for individual animals are shown together with their means ± SEM (*P < 0.01).
