Table 3.
Distribution of G-CSF IR in cortical regions.
| Control |
AD |
|||||||
|---|---|---|---|---|---|---|---|---|
| Neuronal cell bodies |
Fibers |
Neuronal cell bodies |
Fibers |
|||||
| Density | Intensity | Density | Intensity | Density | Intensity | Density | Intensity | |
| Cerebral cortex | ||||||||
| Wernicke's area | ||||||||
| I | ++ | + | ++ | + | 0/++ | 0/++ | 0/++ | 0/++ |
| II | 0/+ | 0/+ | 0/++ | 0/+ | 0 | 0 | 0/++ | 0/+ |
| III | ++ | + | 0/++ | 0/+ | ++ | + | 0/++ | 0/+ |
| IV | 0 | 0 | 0/++ | 0/+ | 0 | 0 | 0/++ | 0/+ |
| V | 0/++ | 0/+ | 0/++ | 0/+ | 0/++ | 0/+ | 0/++ | 0/+ |
| VI | 0 | 0 | 0/++ | 0/+ | 0/+ | 0/+ | 0/++ | 0/+ |
| Frontal pole | ||||||||
| I | ++ | + | 0/+++ | 0/+ | 0/++ | 0/++ | +/++ | + |
| II | 0 | 0 | 0/+++ | 0/+ | 0/+ | 0/+ | +/++ | + |
| III | 0/++ | 0/+ | 0/+++ | 0/+ | +/++ | + | +/++ | + |
| IV | 0/+ | 0/+ | 0/+++ | 0/+ | 0/+ | 0/+ | +/++ | + |
| V | 0/++ | 0/+ | 0/+++ | 0/+ | 0/+ | 0/+ | +/++ | + |
| VI | 0/++ | 0/+ | 0/+++ | 0/+ | 0/+ | 0/+ | +/++ | + |
| Occipital pole | ||||||||
| I | ++ | + | 0/++ | 0/++ | 0/++ | 0/++ | 0/++ | 0/+ |
| II | 0/+ | 0/+ | 0/++ | 0/+ | 0/+ | 0/+ | 0/++ | 0/+ |
| III | 0/+ | 0/+ | 0/++ | 0/+ | 0/++ | 0/+ | 0/++ | 0/+ |
| IV | 0/+ | 0/+ | 0/++ | 0/+ | 0/+ | 0/+ | 0/++ | 0/+ |
| V | 0 | 0 | 0/++ | 0/+ | 0/+ | 0/+ | 0/++ | 0/+ |
| VI | 0/+ | 0/+ | 0/++ | 0/+ | 0/+ | 0/+ | 0/++ | 0/+ |
| Inferior temporal gyrus | ||||||||
| I | ++ | +/++ | 0/++ | 0/+ | ++ | +/++ | 0/++ | 0/+ |
| II | 0/++ | 0/+ | 0/++ | 0/+ | 0/+ | 0/+ | 0/++ | 0/+ |
| III | ++ | + | 0/++ | 0/+ | ++ | + | 0/++ | 0/+ |
| IV | 0/+ | 0/+ | 0/++ | 0/+ | 0/+ | 0/+ | 0/++ | 0/+ |
| V | 0/++ | 0/+ | 0/++ | 0/+ | 0/++ | 0/+ | 0/++ | 0/+ |
| VI | 0/++ | 0/+ | 0/++ | 0/+ | 0/++ | 0/+ | 0/++ | 0/+ |
| Cingulate gyrus | ||||||||
| I | + | + | 0 | 0 | ++ | + | 0/+ | 0/+ |
| II | 0 | 0 | 0 | 0 | 0 | 0 | 0/+ | 0/+ |
| III | ++ | + | 0 | 0 | 0/++ | 0/+ | 0/+ | 0/+ |
| IV | 0 | 0 | 0 | 0 | 0 | 0 | 0/+ | 0/+ |
| V | + | + | + | + | 0/++ | 0/+ | 0/+ | 0/+ |
| VI | 0 | 0 | + | + | 0/++ | 0/+ | 0/+ | 0/+ |
Density: 0: no immunoreactive structures, + up to 10%, ++ 10–50%, +++ more than 50%. Intensity: 0: no immunoreactivity, + faint, ++ moderate, +++ strong. The range of minimum and maximum staining between individual cases is given.