Table 1.
Summaries of patient’s characteristics for CALGB 30002, 30206, and 39808
| 30002 (N = 34) |
30206 (N = 57) |
39808 (N = 9) |
Overall (N =100) |
Fisher’s exact p- value for balance among 3 studies |
||
|---|---|---|---|---|---|---|
| Gender | ||||||
| Male | 16 (47%) | 34 (60%) | 6 (67%) | 56 | 0.4683 | |
| Female | 18 (53%) | 23 (40%) | 3 (33%) | 44 | ||
| Age | ||||||
| Median(min, max) | 62 (45, 78) | 60 (41, 77) | 54 (49, 79) | 61 (41, 79) | 0.8712 | |
| <=59 | 14 (41%) | 25 (44%) | 5(56%) | 44 | ||
| 60–69 | 14 (41%) | 22 (39%) | 2(22%) | 38 | ||
| >=70 | 6 (18%) | 10 (18%) | 2(22%) | 18 | ||
| Race | ||||||
| White | 32 (94%) | 55 (96%) | 9(100%) | 96 | 0.7468 | |
| Black | 2 (6%) | 2 (4%) | 0(0%) | 4 | ||
| Performance | ||||||
| Status | ||||||
| 0 | 15 (44%) | 40 (70%) | 3(33%) | 58 | 0.0147 | |
| 1 | 18 (53%) | 17 (30%) | 6(67%) | 41 | ||
| 2 | 1 (3%) | 0 (0%) | 0(0%) | 1 | ||
| Weight loss | ||||||
| <5% | 21 (62%) | 48 (84%) | 8 (89%) | 77 | 0.1758 | |
| 5% - <10% | 7 (21%) | 4 (7%) | 1(11%) | 12 | ||
| 10%- <20% | 1 (3%) | 3 (5%) | 0 (0%) | 4 | ||
| >=20% | 2 (6%) | 2 (4%) | 0 (0%) | 4 | ||
| Missing | 3 (9%) | 0 (0%) | 0(0%) | 3 | ||
| Pleural Effusion | ||||||
| No | 33 (97%) | 51 (89%) | 9(100%) | 93 | 0.3178 | |
| Yes | 1 (3%) | 6 (11%) | 0(0%) | 7 |
| b Comparisons between included patients and excluded patients who had completed 4, 5 or 6 cycles of treatment | |||||
|---|---|---|---|---|---|
| Excluded & completed 4+ cycles N=78 |
Included N=100 |
Overall N =178 |
Fisher’s exact p-value for comparison between included and excluded |
||
| Gender | |||||
| Male | 33(42%) | 56(56%) | 89 | 0.0963 | |
| Female | 45(58%) | 44(44%) | 89 | ||
| Age | |||||
| Median(min, max) | 62(38,79) | 0.4667 | |||
| <=59 | 35(45%) | 44(44%) | 79 | ||
| 60–69 | 34(44%) | 38(38%) | 72 | ||
| >=70 | 9(12%) | 18(18%) | 27 | ||
| Race | |||||
| White | 70(90%) | 96(96%) | 166 | 0.2162 | |
| Black | 6(8%) | 4(4%) | 10 | ||
| Other | 2(2%) | 0(0%) | 2 | ||
| Performance Status | |||||
| 0 | 38(49%) | 58(58%) | 96 | 0.3997 | |
| 1 | 38(49%) | 41(41%) | 79 | ||
| 2 | 2(2%) | 1(1%) | 3 | ||
| Weight loss | |||||
| <5% | 53(68%) | 76(76%) | 129 | 0.1492 | |
| 5% - <10% | 13(17%) | 12(12%) | 25 | ||
| 10%- <20% | 10(13%) | 4(4%) | 14 | ||
| >=20% | 2(2%) | 4(4%) | 6 | ||
| Missing | 0(0%) | 4(4%) | 4 | ||
| Pleural Effusion | |||||
| No | 76(97%) | 93(93%) | 169 | 0.3022 | |
| Yes | 2(3%) | 7(7%) | 9 | ||