Table 3.
Association of radiation dose-volume parameters and post-treatment grade 3 or greater pulmonary toxicity *
| Variables | Grade 0 – 2 Median (n) |
Grade 3 Median (n) |
Wilcoxon rank-sum test (0–2) vs (3–5) p-value (n, #s Grade(0–2)/ #s Grade (3–5) |
|---|---|---|---|
| Age | 60 (n=97) | 69 (n=3) | p=0.0906 (n=100,97/3) |
| TLV | 3530 (n= 91) | 2565 (n=3) | p=0.0520 (n=94, 91/3) |
| PTV1 | 469 (n=69) | 707 (n=2) | p=0.6653 n=(71, 69/2) |
| GTV | 31 (n=78) | 49 (n=3) | p=0.1407 (n=81, 78/3) |
| PTV1/TLV * 100 | 13 (n=68) | 29 (n=2) | P=0.3718 (n=70, 68/2) |
| Lung V5 | 50 (n=97) | 70 (n=3) | P=0.0944 (n=100, 97/3) |
| Lung V10 | 42 (n=97) | 63 (n=3) | P=0.0718 (n=100, 97/3) |
| Lung V20 | 35 (n=97) | 50 (n=3) | P=0.0379 (n=100,97/3) |
| Lung V40 | 24 (n=97) | 38 (n=3) | P=0.0135 (n=100,97/3) |
| Lung V60 | 13 (n=97) | 25 (n=3) | P=0.0093 (n=100,97/3) |
| Mean Dose (Lung) | 1971 (n=87) | 3110 (n=3) | P=0.0193 (n=90, 87/3) |
| Mean Dose (Heart) | 1715 (n=79) | 3622 (n=3) | P=0.1207 (n=82, 79/3) |
*
No patient experienced grade 4–5 toxicity