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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: Nat Biotechnol. 2010 Dec 19;29(1):51–57. doi: 10.1038/nbt.1739

Figure 5.

Figure 5

HLA haplotypes of P0 determined using DDP. At each of the six classical HLA loci, the experimentally phased SNP haplotypes of P0 and 176 phased SNP haplotypes of CEU trios available from HapMap phase III were placed on a neighbor-joining tree. The two haplotypes of P0 are labeled in red and blue. For haplotypes in the CEU panel with HLA typing data, the four-digit HLA allele is presented next to the sample label. Most of each tree is compressed. Each compressed subtree is labeled with the HLA allele associated with members inside the subtree, if HLA allele information is available. The allelic identities of HLA-B and HLA-C on haplotype 1 were not determined with DDP because CEU individuals with similar SNP haplotypes as P0’s SNP haplotypes did not have HLA typing data at these loci but could be inferred from the results of direct HLA typing of genomic DNA (first row of table). HLA-DQA1 was not directly typed.