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. 2014 May 20;2(5):e12003. doi: 10.14814/phy2.12003

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© 2014 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Percentage of spikes fired in bursts throughout 60 sec traces. Intraburst periods were calculated based on changes in ISI_min where burst initiations and terminations were classified as any periods where ISI_min(n + 1) − ISI_min(n) >2 mV and ISI_min(n + 1) − ISI_min(n) <−2 mV, respectively. Mean values for figures are: Control 0.7 ± 1.2, TCB‐2 + DNQX 10.2 ± 7.8, TCB‐2 + bicuculline 34.7 ± 33.5, and TCB‐2 + DNQX + bicuculline 68.7 ± 9.2. One‐tailed unpaired t‐tests were conducted between groups assuming unequal variance. Asterisks denote statistical significance: *P < 0.05, **P < 0.01, ***P < 0.001.