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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: Connect Tissue Res. 2014 Apr 18;55(3):177–186. doi: 10.3109/03008207.2014.906408

Figure 4. Immunohistochemistry results of significant ECM factors regulated by single or multiple injections of IL-1Ra.

Figure 4

Graphs and representative images showing type I procollagen (a-i) 5 days post-injury after PBS or IL-1Ra treatment. A single injection of IL-1Ra significantly increased type I procollagen (a). Multiple IL-1Ra injections Type I procollagen tended to increase after administration of multiple IL-1Ra injections (a). Representative micrographs show type I procollagen IHC after single injection (low magnification b-c; high magnification f-g) and multiple IL-1Ra (low magnification d-e; high magnification h-i) injections. Values above bars in graphs (a) indicate p-values resulting from Student’s t-tests. Data was considered significant when p< .05. Values are expressed as mean cell numbers ± S.E.M.