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QCMF-significant residue positions are in contact with glucose binding site in human GCK protein (PDB-Entry 1V4S). (A) Red spheres show the structural positions of the glucose binding sites (active sites) and yellow spheres show the localization of significant adjacent residue positions found by QCMF which are in contact with these active sites. The circles indicate clusters of glucose binding sites and their significant adjacent sites.
