Table 2.

852A dose administration

Patient	Total doses received	Max dose received	Number of maximum doses received	Dose reduction	Treatment discontinued	Reason
1	24	1.2	14	No	No
2	12	1.2	5	Yes	Yes	Disease progression
3	9	1.2	3	No	Yes	Disease progression
4	6	1	2	No	Yes	Nausea/vomiting
5	1	0.6	1	No	Yes	EF-15%
6	10	1.2	4	No	Yes	Fatigue
7	5	1	1	No	Yes	Disease progression
8	24	1.2	18	No	No
9	12	1.2	6	No	Yes	Disease progression
10	37	1.2	31	No	During second course	Anorexia, nausea/vomiting
11	24	1.2	2	Yes	No
12	2	0.6	2	No	Yes	Non-ST elevated MI
13	14	1.2	8	No	Yes	Disease progression
14	0					DOD before first dose

DOD dead of disease