Table 5.
Cytokine median values and ranges pre-treatment and 6-h post-treatment dose 1
| Cytokine | N | Median (range) | Median fold change (range) | p value |
|---|---|---|---|---|
| IL-1ra | ||||
| Pre-treatment | 13 | 903.30 (420.37, 4,591.80) | ||
| 6 h after treatment | 12 | 2,981.15 (505.29, 42,000) | ||
| Difference | 12 | 1,902.16 (−60.67, 38,854.80) | 2.6 (0.95, 32.3) | 0.0024* |
| IP-10 | ||||
| Pre-treatment | 13 | 210.60 (71.44, 1,017.52) | ||
| 6 h after treatment | 12 | 1,129.79 (176.12, 5,164.90) | ||
| Difference | 12 | 856.84 (34.53, 4,810.08) | 4.9 (1.1, 21.5) | 0.0005* |
IL-1α, IL-1β, IL-1ra, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-17, ENA-78/CXCL5, FGF-basic, G-CSF, GM-CSF, IFN-γ,MCP-1/CCL2, MIP-1α/CCL3, MIP-1β/CCL4, RANTE S/CCL5, TNF-α, TPo, VEGF, sCD40L, IL-12p70, IL-7, IL-12p40, IL-13, IL-15 and IP-10/CXCL10 were analyzed
The table represents the cytokines that were significantly different between pre and 6 h post 852 dose 1