Table 3.
24 hpf | 48 hpf | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Probe ID | Ensembl Transcript ID | Zebrafish Gene Symbol |
Human Gene Symbol |
DBT Array log2 FC |
DBT QPCR log2 FC |
PYR Array log2 FC |
PYR QPCR log2 FC |
BAA Array log2 FC |
BAA QPCR log2 FC |
DBT Array log2 FC |
DBT QPCR log2 FC |
PYR Array log2 FC |
PYR QPCR log2 FC |
BAA Array log2 FC |
BAA QPCR log2 FC |
A_15_P212366 | ENSDART00000010918 | agt | AGT | 2.6a | 2.71 ± 0.71b | 1.5 | 2.07 ± 1.25 | −0.02 | 0.05 ± 0.87 | --- | --- | --- | --- | --- | --- |
A_15_P104804 | ENSDART00000105896 | atp2a1l | ATP2A1 | −1.13a | −1.82 ± 0.67 | −0.58 | −0.85 ± 0.76 | −0.12 | 0.06 ± 0.85 | --- | --- | --- | --- | --- | --- |
A_15_P120653 | ENSDART00000077511 | ccr9a | CCR9 | 0.04 | 0.41 ± 0.95 | 0.17 | 0.78 ± 0.53 | 0.73 | 1.65 ± 0.49 | −0.23 | 0.2 ± 0.49 | −0.05 | −0.24 ± 0.52 | 1.75a | 1.3 ± 0.27a |
A_15_P170406 | ENSDART00000066439 | ch25h | CH25H | 2.21 | 2.71 ± 1.28b | 2.6a | 2.95 ± 1.09b | 0.07 | 0.96 ± 0.53 | --- | --- | --- | --- | --- | --- |
A_15_P140876 | ENSDART00000017756 | ctsl.1 | CTSL1 | --- | --- | --- | --- | --- | --- | 0.47 | −0.17 ± 0.35 | −0.08 | −0.39 ± 0.09 | 2.08a | 1.68 ± 0.16b |
A_15_P131751 | ENSDART00000038200 | cyp1a | CYP1A1 | 0.61 | −0.03 ± 0.47 | 0.73 | 0.47 ± 0.54 | 4.11a | 4.77 ± 0.43b | 0.25 | 0.81 ± 0.23 | 1.1 | 1.43 ± 0.47b | 5.11a | 6.63 ± 0.32b |
A_15_P554522 | ENSDART00000099870 | cyp1b1 | CYP1B1 | 0.24 | −0.79 ± 0.24 | 0.33 | −0.52 ± 0.51 | 2.87a | 2.37 ± 0.34b | −0.18 | 0.55 ± 0.33 | 0.02 | 0.05 ± 0.61 | 2.46a | 2.55 ± 0.25b |
A_15_P130722 | ENSDART00000019953 | cyp1c1 | −0.78 | −0.34 ± 0.37 | 0.53 | −0.05 ± 0.53 | 2.49a | 2.22 ± 0.41b | 0.18 | −0.22 ± 0.18 | 0.65 | −0.23 ± 0.34 | 4.67a | 4.14 ± 0.44b | |
A_15_P287511 | ENSDART00000016487 | cyp1c2 | −0.21 | −0.29 ± 0.21 | 0.31 | 0 ± 0.19 | 1.74a | 1.59 ± 0.25b | −0.37 | −0.17 ± 0.27 | −0.23 | −0.3 ± 0.3 | 2.51a | 3.12 ± 0.34b | |
A_15_P402330 | ENSDART00000109464 | g0s2 | G0S2 | −1.32a | −1.62 ± 0.38b | −0.77 | −0.47 ± 0.29 | −0.22 | 0.09 ± 0.23 | −0.21 | −0.38 ± 0.52 | −1.02a | −0.75 ± 0.4 | −1.06a | −0.61 ± 0.22 |
A_15_P175986 | ENSDART00000100386 | mstnb | MSTN | −1.84a | −0.66 ± 0.1 | −0.64 | −0.16 ± 0.27 | −1.5a | −0.3 ± 0.24 | --- | --- | --- | --- | --- | --- |
A_15_P168906 | ENSDART00000103784 | si:ch211-202b2.2 | EDN2 | --- | --- | --- | --- | --- | --- | −0.02 | −0.01 ± 0.14 | −0.34 | 0.03 ± 0.31 | −0.94a | −0.75 ± 0.18b |
A_15_P143451 | ENSDART00000025669 | slc16a9b | SLC16A9 | 2.96a | 3.31 ± 0.3b | 2.59a | 2.9 ± 0.42b | 0.16 | 0.28 ± 0.84 | --- | --- | --- | --- | --- | --- |
A_15_P153096 | ENSDART00000130131 | sult6b1 | SULT6B1 | 0.06 | 0.11 ± 0.09 | −0.2 | 0.18 ± 0.29 | 1.02a | 0.96 ± 0.22 | 0.03 | −0.27 ± 0.26 | 0.04 | −0.28 ± 0.18 | 1.42a | 1.03 ± 0.24b |
A_15_P206556 | ENSDART00000017569 | tnfb | TNF | 2.74a | 2.88 ± 1.02b | 3.2a | 3.2 ± 0.63b | 0.59 | 0 ± 0.15 | 1.04 | 0.82 ± 0.24 | 2.47a | 2.3 ± 0.66b | 0.05 | −0.17 ± 0.17 |
Significantly different from vehicle control (One-way ANOVA with Tukey’s post hoc test and 5% FDR, p<0.05)
Significantly different from vehicle control (One-way ANOVA with Tukey’s post hoc test, p< 0.05).