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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: Immunity. 2011 Dec 8;35(6):883–896. doi: 10.1016/j.immuni.2011.11.010

Fig. 1. MYSM1 is essential for B-cell development.

Fig. 1

a-d. Representative flow cytometry profiles of bone marrow (BM), spleen (SP), lymph node (LN) and peripheral blood (PB) from homozygous Mysm1-/-mice and WT littermates (n = 8 per group, ~6 weeks old) to identify total B-cells (B220+CD19+) (a), percent cells expressing IgM and IgD (b) or immature B-cells (B220+IgM+) (c), and T cells (CD3+) (d). Numbers in quadrants indicate percent cells in each.

e. Percents of B220+CD19+ B-cells, CD3+ T-cells, CD3+CD4+ and CD3+CD8+ T-cells in indicated tissues of WT and Mysm1-/-mice (n=4 per group).

f. Percentages of indicated cell numbers from BM of Mysm1-/- mice compared to those from WT mice (n=4). Error bars indicate +SD.