Figure 3.

Extracellular vesicle size dependent diffusion and displacement. A) Diffusion coefficients of exosomes (solid red) and microvesicles (dashed blue) as given by the Stokes-Einstein equation. B) Root-mean-square displacement of exosomes (dashed only lines) and microvesicles (dashed with dotted lines) through an aqueous extracellular environment. C) Representative image of ~100 nm particles visualized using a NTA instrument (NanoSight LM14). Red lines are the diffusional displacement of the particles tracked by the NTA software. Each particle is associated with two numbers, the upper number represents the particle size as calculated using the Stokes-Einstein equation and the lower number represents the particle’s track length.