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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: Osteoarthritis Cartilage. 2011 Jul 29;19(10):1246–1253. doi: 10.1016/j.joca.2011.07.011

Table III.

Differential activation of endogenous COMP and Col2a1 mRNA expression by Sox trio (n = 3)

Mean folds of control (95% CI)
COMP P-value Col2a1 P-value
C20/A4
Control 1.01 (0.87–1.19) – 1.00 (0.99–1.01) –
Sox9 0.76 (0.62–1.03) 0.3696 1.23 (1.19–1.26) 0.0065
Sox5 & 6 1.64 (1.29–2.11) 0.0521 1.25 (1.19–1.30) 0.0129
Sox5, 6, & 9 0.67 (0.44–0.81) 0.0625 95.27 (85.63–114.56) 0.0103
BMSC
Control 1.00 (0.91–1.06) – 1.00 (0.95–1.06) –
Sox9 1.15 (1.05–1.25) 0.0168 28.73 (20.95–36.02) 0.0236
Sox6 1.30 (1.27–1.35) 0.0149 14.14 (11.21–16.19) 0.0123
Sox6 & 9 1.59 (1.39–1.80) 0.0468 7,169 (6,293–7,856) 0.0041