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. 2014 Aug 10;21(5):804–817. doi: 10.1089/ars.2013.5714

FIG. 3.

FIG. 3.

Structures of PEI and bioreducible polymers. Nondegradable linear LPEI and branched bPEI (left top). Bioreducible bPEI derivates (LRx-lPEIy and BCx-lPEIy) (4) based on LPEI and cross-linker (x denotes the molar ratio cross-linker/LPEI, and y denotes the MW (kDa) of the LPEI. For LRx-lPEIy, the molar ratio between linker and LPEI monomers was 0.5%–3%; for BCx-lPEIy, the molar ratio between linker and LPEI monomers was 3%–8%). bPEIS (52) contains a bioreducible diaminoethane system and a nondegradable cross-linker. SS-PAEI (12, 63, 64) consists of poly(amido ethylenimine) with bioreducible disulfide bonds and variable residues for functionalization (right bottom).