Table 1.

Polymorphic variants in NANOS3 identified in POI patients and controls.

		Genotype frequency (%)
Variant	dbSNP id	Patients with POI			Controls
		Wild-type	Heterozygote	Homozygote	Wild type	Heterozygote	Homozygote
c.-23C>T (5′ UTR)	rs897790	60	34.1	5.9	72.5	25.7	1.8
c.353A>G (exon 1, synonymous)	rs2016163	50.6	40	9.4	70	27.4	2.6