(b).
Species | Cells and tissues reported to express TLR2 | Methoda | Information on the level of expression | Reference |
---|---|---|---|---|
Bovine | Monocytes | RT-PCR/FC | Strong | [23, 28] |
Monocyte derived-macrophages | RT-PCR/FC | |||
Alveolar macrophages | RT-PCR/FC | Intermediate | ||
Monocyte derived-DCs | RT-PCR/FC | Weak | ||
CD172+ DCs | RT-PCR/FC | |||
CD172− DCs | RT-PCR/FC | |||
CD21+ B cells | RT-PCR | No signal | [28] | |
| ||||
Ovine | CD14+ monocytes from PBMCs | FC | [23] | |
| ||||
Nilgai and Buffalo | PBMCs, monocytes, DCs, testes, skin | RT-PCR | Higher in Nilgai than Buffalo | [29] |
Buffalo | Kidney, endometrium, bone marrow, trachea | RT-PCR | Higher in endometrium and bone marrow | |
| ||||
Swine | Mesenteric lymph nodes and Peyer's patches | RT-PCR, IHC, FC | Higher than in spleen by RT-PCR | [30] |
Heart, thymus, lung, kidney, skeletal muscle, small intestine | RT-PCR | Lower than in spleen | ||
M cells | IHC, FC | |||
T and B cells | FC | Higher in T cells than in B cells | ||
Monocytes, macrophage, and granulocytes, but not on peripheral blood lymphocytes | FC | [24] | ||
Epithelial cells lining body entries (Lung, jejunum, kidney, liver) | IHC | |||
Alveolar Macrophages | WB | [17] | ||
| ||||
Equine | PBMCs | RT-PCR | [33] | |
Alveolar macrophages | RT-PCR | [31] | ||
Respiratory epithelial tissues | RT-PCR | [32] | ||
| ||||
Chicken | Heart, liver, gizzard, muscle | RT-PCR, WB | Strong | [26] |
Spleen, caecal tonsil, bursa, liver | RT-PCR | Strong | [34] | |
Heterophils, monocytes, macrophages, B and T cells | RT-PCR | [34, 35] | ||
| ||||
Canine | Blood mononuclear cells, lymph node, lung, liver, spleen, bladder, pancreas, small intestine, large intestine, and skin | RT-PCR | [18] | |
Blood neutrophils | RT-PCR | [27] | ||
Blood neutrophils, monocytes | FC | Higher levels | ||
Lymphocytes | FC | Lower levels | ||
| ||||
Feline | Spleen, thymus | RT-PCR | [36] | |
CD4+ T cells, CD8+ T cells, CD21+ B cells | RT-PCR | Higher in B cells than in T cells | ||
BM-DCs | RT-PCR | [37] | ||
Palatoglossal mucosa | RT-PCR | [38] |
aRT-PCR: reverse transcription-PCR; FC: flow cytometry; IHC: immunohistochemistry; WB: Western blot.