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. 2014 Jul 15;9(7):e101826. doi: 10.1371/journal.pone.0101826

Table 1. Characteristics of the Studies Selected (N = 400).

Characteristics n (%)
Funding (n = 400) *
Industry 247 (61.7)
Non-industry 106 (26.5)
Blended 47 (11.8)
Study Phase (n = 400) *
Phase 2 209 (52.3)
Phase 3 130 (32.5)
Phase 4 61 (15.2)
Gender (n = 400) *
Both 356 (89.0)
Female only 31 (7.7)
Male only 13 (3.3)
Age Group (n = 400)
Adult only 332 (83.0)
Child involved 68 (17.0)
Randomization (n = 399) **
Randomized 271 (67.9)
Not randomized 128 (32.1)
Investigator (n = 400)
Non-academia 238 (59.5)
Academia 162 (40.5)
Number of Study Subjects (n = 389) **
Median 98
Mean (SD) 249 (452)
Range 1–5993
Study length (days) (n = 400)
Median 639
Mean (SD) 874 (817)
Range 29–6908

*Phase 3 and 4 were aggregated as “phase 3/4”, non-industry funded and blended studies were aggregated as “non-industry or blended” and female only and male only were aggregated as “male or female only” in the analysis.

**Some data were missing in CTG registry and the total number did not sum up 400.