Table 3.
Demographic and clinical characteristics of patients stratified by clinical outcome
Characteristic | Clinical success group (n = 194) | Clinical failure group (n = 66) | P value |
---|---|---|---|
Mean ± SD age, years |
46.4 ± 19 |
56.2 ± 21 |
<0.05 |
Males, n (%) |
113 (58.2) |
36 (54.5) |
NS |
Comorbidities, n (%) |
|
|
|
Diabetes mellitus |
7 (3.6) |
5 (7.5) |
NS |
Obesity |
9 (4.6) |
3 (4.5) |
NS |
Lifestyle factors, n (%) |
|
|
|
Smoking |
22 (11.3) |
5 (7.5) |
NS |
Alcoholism |
0 (0) |
0 (0) |
NS |
Therapeutic failure risk factors, n (%) |
|
|
|
Age > 65 years |
38 (19.5) |
25 (37.8) |
<0.05 |
Cancer |
8 (4.1) |
8 (12.1) |
<0.05 |
Anemia |
6 (3.1) |
10 (15.2) |
<0.05 |
Liver cirrhosis |
1 (0.5) |
0 (0) |
NS |
Renal failure |
1 (0.5) |
1 (1.5) |
NS |
End stage renal failure |
2 (1.0) |
0 (0) |
NS |
Coagulopathy |
2 (1.0) |
0 (0) |
NS |
Immunosuppression |
1 (0.5) |
1 (1.5) |
NS |
Primary surgical intervention site, n (%) |
|
|
|
Appendix |
132 (68.0) |
30 (45.4) |
<0.05 |
Lower GI tract |
23 (11.8) |
28 (42.4) |
<0.05 |
Upper GI tract |
10 (5.1) |
3 (4.5) |
NS |
Gall-bladder |
13 (6.7) |
1 (1.5) |
NS |
Peritoneal abscess |
13 (6.7) |
3 (4.5) |
NS |
Other |
3 (1.5) |
1 (1.5) |
NS |
Surgical approach, n (%) |
|
|
|
Laparoscopy |
111 (57.2) |
24 (36.3) |
<0.05 |
Laparotomy |
76 (39.2) |
40 (60.6) |
<0.05 |
Percutaneous |
7 (3.6) |
2 (3.0) |
NS |
Antibiotic treatment, n (%) |
|
|
|
Monotherapy |
101 (52.1) |
46 (69.7) |
<0.05 |
Combination therapy |
93 (47.9) |
20 (30.3) |
<0.05 |
Illness severity markers, n (%) |
|
|
|
Parenteral nutrition |
27 (13.9) |
25 (37.8) |
<0.05 |
Central venous catheter |
16 (8.2) |
24 (36.3) |
<0.05 |
Antifungal drugs |
12 (6.2) |
16 (24.2) |
<0.05 |
Enteral nutrition |
10 (5.2) |
12 (18.2) |
<0.05 |
Invasive mechanical ventilation |
6 (3.1) |
14 (21.2) |
<0.05 |
ICU admission, n (%) |
6 (3.1) |
18 (27.3) |
<0.05 |
Mortality rate, n (%) | 0 (0) | 6 (9.1) | NS |
GI, gastrointestinal; ICU, intensive care unit; NS, not significant; SD, standard deviation.