Table 1.
Demographic and clinical characteristics and their correlation with NR2Ab level and NR2Ab 1.8 ng/mL cut-off.
| Variables | Total (n = 56) | NR2Ab level a r | NR2Ab 1.8 ng/mL cut-off a r |
|---|---|---|---|
| PWV (m/s) | 9.3 ± 2.2 | 0.28 ∗ | 0.27 ∗ |
| PWV cut-off | — | 0.42 ∗∗ | 0.43 ∗∗ |
| NR2Ab 1.8 ng/mL cut-off | — | 0.74 ∗∗ | 1.00 |
| Age (years) | 71 ± 8.4 | −0.08 | 0.01 |
| Gender (male) | 40 (71.4%) | −0.26 | −0.32∗ |
| DM [n (%)] | 8 (14.3%) | 0.14 | 0.09 |
| Smoking [n (%)] | 2 (3.6%) | −0.08 | 0.02 |
| BMI (kg/m2) | 27.2 (4.2) | −0.21 | −0.23 |
| SBP (mmHg) | 136 ± 24 | −0.03 | 0.02 |
| DBP (mmHg) | 76 ± 11 | −0.22 | −0.24 |
| PP (mmHg) | 62 ± 15 | 0.11 | 0.21 |
| MAP (mmHg) | 97 ± 12 | −0.11 | −0.15 |
| Cholesterol (mmol/L) | 4.5 ± 1.2 | 0.23 | 0.22 |
| Hypertension [n (%)] |
38 (67.9%) | 0.18 | 0.14 |
| Statin treatment [n (%)] | 38 (67.9%) | 0.10 | 0.02 |
| PVD [n (%)] | 2 (3.6%) | 0.12 | 0.25 |
| EuroSCORE (logistic) | 5.5 ± 4.3 | 0.04 | 0.18 |
| AVA (cm2) | 0.73 ± 0.2 | −0.09 | −0.10 |
| AVMG (mmHg) | 48 ± 13 | 0.00 | −0.06 |
| AVPG (mmHg) | 82 ± 24 | 0.14 | 0.01 |
| EF | 59 ± 15 | 0.22 | 0.06 |
*Correlation is significant at the 0.05 level (2-tailed); **correlation is significant at the 0.01 level (2-tailed). aCorrelation coefficient, bold values indicate statistical significance. Abbreviations: AVA, aortic valve area; AVMG, aortic valve mean gradient; AVPG, aortic valve peak gradient; BMI, body mass index; DBP, diastolic blood pressure; DM, diabetes mellitus; EF, Ejection fraction; MAP, mean arterial blood pressure; NR2Ab, N-methyl-D-aspartate (NMDA) receptor antibodies; PP, pulse pressure; PVD, peripheral vascular disease; PWV, pulse wave velocity; SBP, systolic blood pressure.