Table 2.
Simple and multiple linear regression analysis to identify variables that independently predict NR2Ab level.
| Predictors | NR2Ab level beta (P value) |
|---|---|
| Simple linear regression | |
| PWV value | 0.27 (0.05) |
| PWV cut-off | 0.39 (<0.01) |
| Age | −0.05 (0.71) |
| Gender (male) | −0.27 (0.05) |
| DM | 0.08 (0.57) |
| Smoking | −0.12 (0.38) |
| BMI (kg/m2) | −0.2 (0.15) |
| MAP (mmHg) | −0.16 (0.26) |
| Cholesterol (mmol/L) | 0.09 (0.67) |
| EuroSCORE (logistic) | 0.07 (0.49) |
| AVA (cm2) | −0.09 (0.55) |
| AVMG (mmHg) | −0.01 (0.92) |
| AVPG (mmHg) | −0.06 (0.66) |
| EF | 0.03 (0.83) |
|
| |
| Multiple linear regression (Model 1) | |
| PWV value | 0.37 (0.02) |
| Age | −0.25 (0.12) |
| Gender (male) | −0.21 (0.12) |
|
| |
| Multiple linear regression (Model 2) | |
| PWV cut-off | 0.37 (<0.01) |
| Age | −0.09 (0.46) |
| Gender (male) | −0.21 (0.11) |
Values are shown as standardized beta coefficient (P value); bold values indicate statistical significance. Abbreviations: AVA, aortic valve area; AVMG, aortic valve mean gradient; AVPG, aortic valve peak gradient; BMI, body mass index; DM, diabetes mellitus; EF, Ejection fraction; MAP, mean arterial blood pressure; NR2Ab, N-methyl-D-aspartate (NMDA) receptor antibodies; PWV, pulse wave velocity.