Table 2. Computational predictions.

	Method
	FIRST	GNM	Both
No. of key residues theoretically identified	45	16	52
Fraction also studied by experiments	34/45	14/16	39/52
Fraction correctly observed to cause misfolding	31/34	11/14	35/39
Fraction of them that cause complete misfolding	26/31	5/11	26/35