Table 1.
Summary of clinical and cytogenetic characteristics of the CLL cases included in the present study.
| Patient characteristics (n = 55) | |
|---|---|
| Age (years) | 71 (47–92) |
| Male | 30 (54.5%) |
| Binet stage | |
| A | 49 (89.1%) |
| B | 5 (9.1%) |
| C | 1 (1.8%) |
| White blood cell count (×109/L) | 28.6 (7.30–240.0) |
| Lymphocyte count (×109/L) | 23.2 (5.6–233) |
| Hemoglobin (g/L) | 13.8 (9.1–16.8) |
| Platelet count (9109/L) | 189.0 (20.0–373.0) |
| Lactate dehydrogenase (U/L) | 358.0 (115–1086.0) |
| β2-Microglobulin (mg/L) | 2.3 (1.0–6.54) |
| ZAP70 positive∗ (n = 37) | 22 (59.4%) |
| CD38 positive∗ (n = 45) | 12 (26.6%) |
| FISH abnormalities | |
| del(13q14) | 18 (32.7%) |
| Trisomy 12 | 8 (14.5%) |
| del(11q22) | 6 (11.0%) |
| del(17p13) | 6 (11.0%) |
| Normal FISH | 17 (31.0%) |
Values are given as median (range) or number (%).
*Positivity was considered when ZAP70 > 20% and CD38 > 30%.