Table 3.
|
Univariable analysis |
Multivariable analysis
^
|
||
---|---|---|---|---|
Variable | HR | 95% CI | HR | 95% CI |
Sex |
|
|
|
|
Female |
1 |
|
1 |
|
Male |
1.41 |
0.91-2.17 |
1.73 |
1.06-2.81 |
Age (years) |
|
|
|
|
≤35 |
1 |
|
1 |
|
36-45 |
1.64 |
0.99-2.72 |
1.05 |
0.60-1.82 |
>45 |
1.91 |
1.14-3.23 |
1.41 |
0.80-2.48 |
BMI (kg/m2) |
|
|
|
|
Normal (18.5-24.9) |
1 |
|
1 |
|
Underweight (<18.5) |
2.05 |
1.27-3.29 |
1.12 |
0.64-1.96 |
Overweight (25.0-29.9) |
0.21 |
0.10-0.44 |
0.34 |
0.15-0.76 |
Obese (≥30.0) |
0.41 |
0.20-0.86 |
0.91 |
0.42-2.00 |
CD4 count (cells/μL) |
|
|
|
|
≥200 |
1 |
|
1 |
|
<200 |
3.35 |
2.18-5.15 |
1.20 |
0.68-2.09 |
HIV viral load (copies/mL) |
|
|
|
|
<10,000 |
1 |
|
1 |
|
10,000-100,000 |
1.95 |
1.02-3.69 |
1.21 |
0.62-2.37 |
>100,000 |
4.04 |
2.29-7.10 |
1.55 |
0.81-2.98 |
Clinical AIDS |
|
|
|
|
No |
1 |
|
1 |
|
Yes |
3.64 |
2.37-5.60 |
1.17 |
0.68-2.02 |
Received ART |
|
|
|
|
No |
1 |
|
1 |
|
Yes |
0.65 |
0.45-0.95 |
0.51 |
0.33-0.80 |
Anemia: Hb (g/dL) |
|
|
|
|
No (≥12.0 women, ≥13.0 men) |
1 |
|
1 |
|
Mild (10.0-11.9 women, 10.0-12.9 men) |
3.41 |
2.00-5.80 |
2.53 |
1.35-4.74 |
Moderate (8.0-9.9) |
10.41 |
6.03-17.98 |
6.51 |
3.25-13.06 |
Severe (<8.0) | 14.40 | 7.86-26.38 | 9.06 | 4.16-19.72 |
*Cox proportional hazards regression.
^n = 1,333. Excluded patients (n = 153) had missing values in any of the variables included in the model: BMI = 115; CD4 count = 33; HIV viral load = 27.
BMI, body mass index; ART, antiretroviral treatment; Hb, hemoglobin level; HR, hazard ratio; CI, confidence interval.