Table 1.
Effect of various treatments on the mean area under curve (AUC) of blood glucose levels in rats.
| Tested compound(s) |
% reduction in blood glucose compared to control | |
|---|---|---|
| SLM | STZ | |
| Amaryl [Standard drug] |
27.7 a | 30.4 a |
| [Ia] | 17.4 a | 33.3 a |
| [Ib] | 10.9 a | NA |
| [Ic] | 18 a | 35.3 a |
| [Id] | NA | NA |
| [Ie] | 16.7 a | 29.5 a |
| [IVg] | 13 a | 11.2 a |
| [VIf] | NA | NA |
| [VIIa] | NA | NA |
| [VIIb] | NA | NA |
| [VIIf] | NA | NA |
| [VIIIa] | NA | NA |
| [VIIIf] | NA | NA |
NA = not active.
aConsidered significant compared to control (P ≤ 0.05).
SLM: Sucrose-Loaded Model; STZ: Streptozotocin model of diabetes.