. 2014 May 7;57(11):4834–4848. doi: 10.1021/jm500361r

Table 1. Screening Data for R³ Variants of 1.

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Data not obtained due to low solubility.

EC₅₀ values are an average of two replicates, with SD less than 0.1 log unit.

SD was less than 0.2 log units.

SD was over 1 log unit.

Selectivity = TC₅₀/EC₅₀.

Stock concentration: 2.5 mM.

Table 1. Screening Data for R3 Variants of 1.