Table 1. Summary of the previously selected 96 genes by GANN.
GANN rank | Symbol | Image Id. | GeneID | Truncated p-value for each cancer | |||
EWS | BL | NB | RMS | ||||
1 | MLLT11 | 812105 | 10962 | 8.65×10−12 | 4.12×10−16 | 7.27×10−17 | 1.33×10−10 |
2 | IGF2 | 207274 | 3481 | 1.03×10−07 | 5.65×10−11 | 7.74×10−06 | 4.78×10−09 |
3 | FCGRT | 770394 | 2217 | 1.03×10−13 | 6.87×10−13 | 5.69×10−10 | 2.27×10−07 |
4 | CAV1 | 377461 | 857 | 5.21×10−11 | 1.00×10−10 | 1.02×10−08 | 8.49×10−08 |
5 | FGFR4 | 784224 | 2264 | 5.20×10−08 | 5.44×10−08 | 2.90×10−08 | 8.32×10−11 |
6 | CD99 | 1435862 | 4267 | 8.12×10−12 | 6.96×10−13 | 8.43×10−09 | 1.04×10−05 |
7 | IGF2 | 296448 | 3481 | 1.33×10−07 | 9.71×10−10 | 5.37×10−05 | 7.89×10−09 |
8 | MAP1B | 629896 | 4131 | 1.30×10−05 | 4.24×10−11 | 1.90×10−07 | 1.41×10−04 |
9 | KDSR | 814260 | 2531 | 2.11×10−09 | 2.49×10−08 | 1.13×10−07 | 8.03×10−08 |
10 | FNDC5 | 244618 | 252995 | 2.53×10−07 | 4.58×10−09 | 3.63×10−06 | 2.13×10−08 |
11 | CDH2 | 325182 | 1000 | 9.87×10−07 | 4.86×10−07 | 2.95×10−08 | 1.41×10−04 |
12 | OLFM1 | 52076 | 10439 | 3.29×10−08 | 2.29×10−10 | 1.26×10−03 | 1.77×10−08 |
13 | RCVRN | 383188 | 5957 | 1.00×10−07 | 4.69×10−14 | 8.68×10−08 | 4.22×10−03 |
14 | PTPN13 | 866702 | 5783 | 2.74×10−08 | 9.53×10−09 | 1.26×10−06 | 2.33×10−07 |
15 | HLA-DMA | 183337 | 3108 | 3.76×10−04 | 1.90×10−07 | 1.15×10−06 | 2.84×10−04 |
16 | MYL4 | 461425 | 4635 | 8.30×10−06 | 1.03×10−06 | 2.28×10−06 | 1.25×10−06 |
17 | SGCA | 796258 | 6442 | 1.83×10−07 | 1.02×10−06 | 5.97×10−07 | 2.05×10−08 |
18 | GAP43 | 44563 | 2596 | 1.03×10−04 | 1.71×10−05 | 3.22×10−05 | 9.14×10−05 |
19 | PSMB8* | 624360 | 5696 | 2.76×10−03 | 1.72×10−06 | 2.00×10−05 | 1.16×10−06 |
20 | PMS2L12* | 878652 | 392713 | 2.25×10−03 | 4.03×10−11 | 3.34×10−07 | 9.49×10−04 |
21 | EHD1* | 745019 | 10938 | 1.13×10−05 | 1.38×10−09 | 2.90×10−04 | 1.45×10−03 |
22 | TNNT2 | 298062 | 7139 | 3.20×10−05 | 1.70×10−05 | 1.97×10−05 | 1.91×10−05 |
23 | CBX1* | 786084 | 10951 | 3.86×10−08 | 1.76×10−03 | 1.86×10−09 | 2.85×10−03 |
24 | RBM38 | 814526 | 55544 | 2.84×10−05 | 2.50×10−07 | 1.06×10−09 | 2.41×10−03 |
25 | TNNT1 | 1409509 | 7138 | 4.90×10−05 | 4.05×10−07 | 5.91×10−06 | 3.63×10−06 |
26 | CRMP1 | 878280 | 1400 | 1.12×10−04 | 2.46×10−11 | 4.80×10−07 | 1.90×10−03 |
27 | HLA-DQA1 | 80109 | 3117 | 1.46×10−03 | 1.80×10−05 | 2.67×10−05 | 2.64×10−04 |
28 | DPYSL4 | 395708 | 10570 | 7.62×10−04 | 1.63×10−10 | 3.05×10−06 | 5.67×10−05 |
29 | PIM2 | 1469292 | 11040 | 2.74×10−03 | 6.31×10−06 | 9.72×10−06 | 1.36×10−05 |
30 | CTNNA1 | 21652 | 1495 | 1.09×10−05 | 5.03×10−11 | 1.13×10−06 | 8.77×10−04 |
31 | SELENBP1 | 80338 | 8991 | 2.12×10−07 | 2.77×10−10 | 1.46×10−08 | 7.56×10−04 |
32 | ELF1 | 241412 | 1997 | 7.03×10−04 | 4.75×10−05 | 5.19×10−06 | 9.91×10−04 |
33 | KIF3C | 784257 | 3797 | 4.80×10−03 | 8.36×10−11 | 1.90×10−05 | 3.69×10−05 |
34 | GYG2 | 43733 | 8909 | 9.70×10−07 | 5.56×10−08 | 8.77×10−06 | 1.03×10−05 |
35 | LSP1* | 143306 | 4046 | 1.22×10−05 | 4.34×10−10 | 4.77×10−04 | 6.24×10−07 |
36 | MT1L | 297392 | 4500 | 2.20×10−03 | 2.50×10−06 | 1.84×10−04 | 7.29×10−04 |
37 | CHD3* | 379708 | 1107 | 1.99×10−07 | 4.37×10−09 | 1.09×10−06 | 4.37×10−04 |
38 | EST (CDK6) | 295985 | 1021 | 3.08×10−10 | 3.26×10−03 | 2.66×10−06 | 1.63×10−04 |
39 | TNFAIP6 | 357031 | 7130 | 7.93×10−07 | 1.92×10−07 | 3.07×10−06 | 1.34×10−05 |
40 | WAS* | 236282 | 7454 | 7.36×10−04 | 7.88×10−08 | 3.27×10−07 | 1.10×10−03 |
41 | GAS1 | 365826 | 2619 | 1.72×10−04 | 4.78×10−11 | 4.69×10−09 | 2.04×10−03 |
42 | HCLS1 | 767183 | 3059 | 1.42×10−03 | 6.05×10−06 | 3.06×10−06 | 1.66×10−04 |
43 | MYO1B | 377048 | 4430 | 2.41×10−05 | 2.77×10−15 | 5.34×10−07 | 1.71×10−02 |
44 | ARPC1B* | 626502 | 10095 | 1.37×10−03 | 8.58×10−05 | 1.49×10−04 | 1.47×10−03 |
45 | HOXB7* | 1434905 | 3217 | 4.75×10−07 | 4.65×10−06 | 1.80×10−11 | 1.89×10−02 |
46 | PRKAR2B | 609663 | 5577 | 3.77×10−04 | 2.19×10−05 | 4.23×10−03 | 1.16×10−07 |
47 | G6PD* | 768246 | 2539 | 1.67×10−05 | 2.72×10−03 | 7.13×10−06 | 5.18×10−04 |
48 | GATA2 | 135688 | 2624 | 3.42×10−03 | 5.37×10−08 | 1.67×10−05 | 1.01×10−05 |
49 | CSDA* | 810057 | 8531 | 3.77×10−04 | 2.10×10−02 | 4.99×10−10 | 7.21×10−04 |
43 | MYO1B | 308231 | 4430 | 3.59×10−05 | 2.84×10−11 | 5.94×10−06 | 1.31×10−02 |
51 | EID1* | 244637 | 23741 | 2.25×10−03 | 4.54×10−05 | 5.89×10−07 | 7.23×10−04 |
52 | PSMB10* | 68977 | 5699 | 1.24×10−03 | 2.80×10−05 | 3.74×10−04 | 1.76×10−03 |
53 | FHL3* | 796475 | 2275 | 2.56×10−05 | 3.26×10−11 | 4.42×10−07 | 5.07×10−03 |
54 | ITPR3* | 435953 | 3710 | 1.31×10−03 | 8.08×10−05 | 1.15×10−07 | 1.22×10−06 |
55 | DPYSL2 | 841620 | 1808 | 2.99×10−05 | 4.26×10−15 | 2.83×10−04 | 5.63×10−07 |
56 | BIN1 | 788107 | 274 | 2.93×10−05 | 2.53×10−07 | 3.05×10−03 | 1.97×10−05 |
57 | PFN2 | 486110 | 5217 | 5.41×10−03 | 1.02×10−15 | 9.16×10−06 | 2.33×10−02 |
58 | TLE2 | 1473131 | 7089 | 2.88×10−07 | 5.70×10−09 | 2.24×10−08 | 1.06×10−03 |
59 | PGAM2* | 283315 | 5224 | 3.25×10−03 | 1.21×10−05 | 2.51×10−02 | 5.78×10−08 |
60 | ISG20* | 740604 | 3669 | 9.18×10−04 | 1.04×10−04 | 1.26×10−04 | 7.18×10−04 |
61 | RDX* | 740554 | 5962 | 6.12×10−07 | 4.86×10−11 | 2.57×10−05 | 1.62×10−03 |
62 | PPP1R18* | 208699 | 170954 | 1.94×10−07 | 2.46×10−06 | 3.19×10−03 | 3.19×10−03 |
63 | CCND1 | 841641 | 595 | 6.10×10−04 | 1.67×10−09 | 2.10×10−03 | 3.21×10−06 |
64 | SMPD1* | 729964 | 6609 | 3.03×10−05 | 2.00×10−08 | 1.07×10−04 | 2.74×10−03 |
65 | MEIS3P1* | 450152 | 4213 | 3.42×10−04 | 2.82×10−10 | 7.84×10−06 | 3.17×10−03 |
66 | MYH10* | 823886 | 4628 | 2.77×10−03 | 7.30×10−13 | 4.38×10−06 | 1.72×10−02 |
67 | IFITM3 | 809910 | 10410 | 1.45×10−03 | 2.50×10−11 | 6.00×10−09 | 5.59×10−04 |
68 | ARSB* | 502055 | 411 | 2.91×10−04 | 9.78×10−10 | 2.01×10−02 | 4.32×10−03 |
69 | BCKDHA* | 740801 | 593 | 1.62×10−05 | 4.15×10−11 | 9.91×10−06 | 1.08×10−02 |
70 | NF2* | 769716 | 4771 | 3.40×10−04 | 3.62×10−07 | 6.50×10−09 | 9.26×10−08 |
71 | CLEC3B* | 345553 | 7123 | 1.24×10−03 | 2.45×10−04 | 1.07×10−03 | 2.73×10−03 |
72 | HSPB2 | 324494 | 3316 | 1.77×10−02 | 1.37×10−09 | 2.10×10−09 | 1.74×10−06 |
73 | NFKB1* | 789357 | 4790 | 2.05×10−05 | 4.94×10−05 | 1.92×10−05 | 1.31×10−02 |
74 | GNA11* | 221826 | 2767 | 4.08×10−07 | 1.12×10−14 | 8.04×10−04 | 8.58×10−03 |
75 | IGF2 | 245330 | 3481 | 7.93×10−04 | 4.43×10−04 | 8.16×10−04 | 7.51×10−04 |
76 | APLP1 | 289645 | 333 | 1.39×10−03 | 1.10×10−11 | 1.18×10−05 | 8.82×10−08 |
77 | NFIC* | 265874 | 4782 | 1.18×10−04 | 3.84×10−09 | 2.50×10−05 | 1.90×10−02 |
78 | TEAD4* | 346696 | 7004 | 1.61×10−02 | 1.37×10−09 | 1.92×10−05 | 9.80×10−06 |
79 | HLA-DPB1 | 840942 | 3115 | 3.38×10−02 | 7.46×10−06 | 4.75×10−05 | 8.64×10−04 |
80 | HMGA1* | 782811 | 3159 | 3.37×10−04 | 7.05×10−05 | 5.88×10−04 | 8.40×10−07 |
81 | MEST* | 898219 | 4232 | 1.06×10−05 | 2.25×10−06 | 5.69×10−05 | 1.20×10−06 |
82 | PTPN12* | 774502 | 5782 | 1.32×10−07 | 4.28×10−07 | 2.82×10−05 | 9.16×10−05 |
83 | IGLL1* | 344134 | 3543 | 2.55×10−03 | 7.44×10−05 | 7.19×10−06 | 3.55×10−02 |
84 | PTTG1IP* | 505491 | 754 | 5.37×10−06 | 1.63×10−12 | 4.99×10−03 | 1.83×10−03 |
85 | AKAP7* | 195751 | 9465 | 9.97×10−04 | 1.06×10−02 | 9.20×10−04 | 1.05×10−03 |
86 | SERPINH1* | 142788 | 871 | 1.73×10−02 | 3.87×10−11 | 3.42×10−04 | 1.14×10−04 |
87 | SEPT4* | 66714 | 5414 | 8.07×10−04 | 3.62×10−07 | 2.87×10−04 | 5.90×10−05 |
88 | CITED2* | 491565 | 10370 | 5.18×10−09 | 9.60×10−10 | 8.45×10−04 | 1.00×10−05 |
89 | TXNRD1* | 789376 | 7296 | 3.23×10−03 | 3.25×10−02 | 2.39×10−06 | 6.32×10−07 |
90 | EST (RND3) | 784593 | 390 | 1.92×10−06 | 1.30×10−13 | 1.51×10−04 | 7.13×10−04 |
91 | TRIP6* | 811108 | 7205 | 3.74×10−07 | 4.99×10−10 | 3.88×10−08 | 3.27×10−02 |
92 | EST (YAP1) | 308163 | 10413 | 3.09×10−05 | 7.70×10−16 | 4.73×10−09 | 8.68×10−04 |
93 | TAF15* | 1474955 | 8148 | 6.55×10−03 | 1.38×10−05 | 2.34×10−03 | 3.45×10−02 |
94 | RXRG* | 358433 | 6258 | 2.31×10−02 | 1.70×10−08 | 5.13×10−07 | 2.87×10−04 |
95 | SERPING1 | 756556 | 710 | 2.82×10−03 | 2.01×10−09 | 2.45×10−05 | 7.04×10−03 |
96 | MYL1* | 628336 | 4632 | 1.74×10−03 | 1.72×10−03 | 2.51×10−02 | 1.51×10−03 |
*indicates complement genes. Truncated p-value is the product of p-value of the gene expression value by its rank order in the GANN model and subsequently adjusted using Benjamini and Hochberg false discovery rate.