Table 5.
Cytokine level patterns in children with HLH, sepsis, infectious mononucleosis, and healthy controls
IFNγ | IL-10 | IL-6 | |
---|---|---|---|
HLH |
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Sepsis |
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Infectious mononucleosis |
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Healthy controls | ↔ | ↔ | ↔ |
Adapted from Tang Y et al, Br J Haematol 2008; 143: 84-91
IFNγ >75 pg/mL and IL-10 > 60 pg/mL have 98.9% sensitivity and 93% specificity for HLH