Table 1. Variants identified by whole genome sequencing of 12 isoniazid-resistant and 17 isoniazid-susceptible Mycobacterium tuberculosis isolates.
| Mutation type | Resistant and Susceptible isolates* | Resistant isolates only | Susceptible isolates only |
| All (n = 8087) | 1949 | 1054 | 5084 |
| Coding | 1669 | 928 | 4392 |
| Synonymous | 573 | 289 | 1552 |
| Nonsynonymous | 977 | 565 | 2397 |
| Nonsense | 14 | 9 | 57 |
| Insertions/Deletions | 105 | 65 | 386 |
| Non-coding (intergenic) | 280 | 126 | 692 |
* Variants that can be found in both isoniazid-resistant and -susceptible isolates.