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. 2004 May 3;101(19):7469–7474. doi: 10.1073/pnas.0401704101

Fig. 4.

Fig. 4.

Purea in the IMCD of UT-A1/3-/- mice. (A) Effect of 0.1 nM AVP on Purea. Five tubules from age-matched wild-type and UT-A1/3-/- littermates were perfused for each group. *, Significant change between groups. (B) Effect of 0.25 mM phloretin on Purea in the presence of AVP. Symbols represent a significant change in Purea from the preceding perfusion group. Tubules from five age-matched wild-type and UT-A1/3-/- littermates were perfused for each group. (C) The effect of 0.1 nM AVP on transepithelial, osmotic water permeability (Pf) in isolated perfused IMCD segments of UT-A1/3-/- mice. Six tubules were perfused for each group. *, Significant change between groups.