Fig. 2.
Weaker orientation selectivity in nob V1. A: responses to different stimulus directions of V1 cells in WT (top) and nob (bottom) mice. Polar plots (right) indicate orientation selective responses (radius = magnitude). B: normalized response tuning curves in WT and nob mice (WT, n = 66, nob, n = 97 cells). C: cumulative distribution of orientation selectivity index (OSI) in WT and nob mice. D: orientation selectivity quantified by the global OSI (gOSI). E: a cumulative plot showing similar direction selectivity indexes (DSI) in WT and nob mice. F: response at the preferred orientation. G: increased responses to the null orientation in nob mice. All bars indicate means + SE. *P < 0.05, **P < 0.01, and ***P < 0.001.