Table 5.

Criteria used to build a prognostic score for patient selection for RFA treatment of liver-only CLM in the context of effective modern-agent systemic therapies

Variable	Reference category	Points
Systemic therapy	Objective response1	1
Number of CLM	≤ 3 CLM	1
Maximum size of CLM	≤ 3 cm2	1
CEA level	≤ 100 ng/mL	1

Abbreviations: CEA, carcinoembryonic antigen; CLM, colorectal liver metastases; RFA, radiofrequency ablation.

¹RECIST-defined response to the immediate preceding systemic therapy regimen before RFA treatment. ²after decrease of ≥30% in size following the immediate preceding systemic therapy regimen before RFA treatment.