Table 2.

Effects of nonspecific icv CRF-R manipulation on nonmaternal behaviors under stress conditions on LD 5

ago, Agonist; ant, antagonist.

The occurrence of all off-nest behaviors was scored for 60 min before and for 60 min after the combined infusion with the maternal defense test (indicated by the dotted line). Off-nest behavior is further divided into locomotion (including digging/burrowing and any explorative behavior in the home cage), self-grooming, and sleeping/resting. For details on treatments, see legend to Figure 1. Data are presented as mean ± SEM. n = 6–7 per group.

**p ≤ 0.01 versus VEH;

++p ≤ 0.01 versus previous time point (two-way ANOVA for repeated measures; factors: time × treatment).