Table 2.
Correlation of inflammatory-cell infiltration with clinicopathologic features of the 36 SmCEC patients.
| Features | Macrophages | Eosinophils | Neutrophils | Lymphocytes | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Low | High | p | Low | High | p | Low | High | p | Low | High | p | |||||||||
| Sex | ||||||||||||||||||||
| Male | 12 | 13 | 1.000 | 12 | 13 | 1.000 | 12 | 13 | 1.000 | 13 | 12 | 1.000 | ||||||||
| Female | 6 | 5 | - | 6 | 5 | - | 6 | 5 | - | 5 | 6 | - | ||||||||
| T stage | ||||||||||||||||||||
| T1 + T2 | 9 | 13 | 0.305 | 12 | 10 | 0.733 | 11 | 11 | 1.000 | 12 | 10 | 0.733 | ||||||||
| T3 + T4 | 9 | 5 | - | 6 | 8 | - | 7 | 7 | - | 6 | 8 | - | ||||||||
| pTNM stage | ||||||||||||||||||||
| I + II | 9 | 15 | 0.075 | 13 | 11 | - | 13 | 11 | 0.725 | 13 | 11 | 0.725 | ||||||||
| III + IV | 9 | 3 | - | 5 | 7 | - | 5 | 7 | - | 5 | 7 | - | ||||||||
| Location of the primary tumor | ||||||||||||||||||||
| Lt | 5 | 5 | 1.000 | 5 | 5 | 1.000 | 5 | 5 | 0.273 | 5 | 5 | 1.000 | ||||||||
| Mt | 12 | 11 | - | 12 | 11 | - | 10 | 13 | - | 12 | 11 | - | ||||||||
| Ut | 1 | 2 | - | 1 | 2 | - | 3 | 0 | - | 1 | 2 | - | ||||||||
| Macroscopic tumor type | ||||||||||||||||||||
| Ulcerative | 8 | 6 | 0.345 | 8 | 6 | 0.922 | 8 | 6 | 0.150 | 7 | 7 | 0.056 | ||||||||
| Medullary | 8 | 6 | - | 7 | 7 | - | 4 | 10 | - | 4 | 10 | - | ||||||||
| Intraluminal | 0 | 3 | - | 1 | 2 | - | 3 | 0 | - | 3 | 0 | - | ||||||||
| Mushroom | 2 | 3 | - | 2 | 3 | - | 3 | 2 | - | 4 | 1 | - | ||||||||
| N stage | ||||||||||||||||||||
| N0 | 3 | 11 | 0.015 * | 5 | 9 | 0.305 | 7 | 7 | 1.000 | 7 | 7 | 1.000 | ||||||||
| N1+N2 | 15 | 7 | - | 13 | 9 | - | 11 | 11 | - | 11 | 11 | - | ||||||||
| Age, years | ||||||||||||||||||||
| ≤60 | 10 | 9 | 1.000 | 9 | 10 | 1.000 | 11 | 8 | 0.505 | 12 | 7 | 0.181 | ||||||||
| >60 | 8 | 9 | - | 9 | 8 | - | 7 | 10 | - | 6 | 11 | - | ||||||||
| Tumor size, cm | ||||||||||||||||||||
| ≤4 | 8 | 12 | 0.315 | 13 | 7 | 0.092 | 10 | 10 | 1.000 | 10 | 10 | 1.000 | ||||||||
| >4 | 10 | 6 | - | 5 | 11 | - | 8 | 8 | - | 8 | 8 | - | ||||||||
Abbreviations: T stage, pathologic stage based on tumor size; N stage, pathologic stage based on lymph node involvement; Lt, lower thoracic esophagus; Mt, middle thoracic esophagus; Ut, upper thoracic esophagus; * p < 0.05. TNM staging: A cancer staging system in which T describes the size of the primary tumor and whether it has invaded nearby tissue, N describes regional lymph nodes involvement, and M describes distant metastasis.