Table 1.
Distributions of selected variables in HCV-infection patients and healthy controls.
| Variables | Controls | Cases | p | |
|---|---|---|---|---|
| Healthy Controls n = 342 (%) | Anti-F Negative n = 186 (%) | Anti-F Positive n = 516 (%) | ||
| Age, year | 56.97 ± 8.34 | 55.35 ± 7.46 | 57.61 ± 7.58 | 0.003 * |
| Sex | 0.057 * | |||
| Females | 228 (66.7) | 142 (76.3) | 352 (68.2) | |
| Males | 114 (33.3) | 44 (23.7) | 164 (31.9) | |
| ALT (UL) | 22.83 ± 7.36 | 26.05 ± 14.02 | 59.04 ± 43.06 | <0.001 * |
| AST (UL) | 24.56 ± 6.65 | 29.61 ± 17.02 | 54.14 ± 37.16 | <0.001 * |
| PLT count (×109/L) | 194.25 ± 39.42 | 182.21 ± 45.93 | 168.64 ± 51.47 | <0.001 * |
| HCV RNA (×106 copies/mL) | – | 3.19 ± 2.72 | 3.04 ± 3.52 | 0.925 ** |
| HCV genotype | 0.077 ** | |||
| 1a | – | 48 (25.9) | 129 (25.0) | |
| 1b | – | 94 (50.5) | 301 (58.3) | |
| Non-1 | 44 (23.7) | 86 (16.7) | ||
| Stage of liver fibrosis | <0.001 # | |||
| F0 | – | 20 (10.8) | 19 (3.7) | |
| F1 | – | 108 (58.1) | 229 (44.4) | |
| F2 | – | 29 (15.6) | 96 (18.6) | |
| F3 | – | 20 (10.8) | 96 (18.6) | |
| F4 | – | 9 (4.8) | 76 (14.7) | |
Data were expressed as mean ± standard deviation. Abbreviation: HCV, hepatitis C virus; ALT, alanine aminotransferase; AST, aspartate aminotransferase; PLT, platelet; F0, no fibrosis; F1, mild fibrosis; F2, moderate fibrosis; F3, severe fibrosis; F4, cirrhosis; * p values were given by chi-square among the group of controls and cases; ** p values were given by chi-square between the group of anti-F negative and anti-F positive; # p value was given by Mantel-Haenszel method.