Table 6.
Distribution of HLA-DPA1-HLA-DPB1 haplotypes among the group of anti-F negative patients, anti-F positive patients and healthy controls.
| Haplotype | Anti-F Positive (%) | Anti-F Negative (%) | Healthy Controls (%) | Cases † vs. Healthy Controls | Anti-F Positive vs. Anti-F Negative | ||
|---|---|---|---|---|---|---|---|
| OR (95% CI) * | p * | OR (95% CI) * | p * | ||||
| DPB1*0402-DPA1*0103 | 6.8 | 8.6 | 7.9 | 0.91 (0.71–1.16) | 0.440 | 0.77 (0.57–1.05) | 0.101 |
| DPB1*0402-DPA1*0202 | 7.5 | 5.6 | 8.2 | 0.84 (0.66–1.07) | 0.149 | 1.35 (0.95–1.92) | 0.096 |
| DPB1*0501-DPA1*0103 | 7.8 | 9.1 | 5.2 | 1.60 (1.21–2.11) | 0.001 | 0.84 (0.62–1.12) | 0.235 |
| DPB1*0501-DPA1*0201 | 1.6 | 1.3 | 1.6 | 0.91 (0.54–1.53) | 0.713 | 1.16 (0.57–2.36) | 0.691 |
| DPB1*0501-DPA1*0202 | 21.1 | 21.6 | 24.6 | 0.83 (0.71–0.97) | 0.017 | 0.97 (0.79–1.19) | 0.768 |
| DPB1*0401-DPA1*0103 | 3.2 | 4.3 | 4.6 | 0.74 (0.54–1.03) | 0.072 | 0.74 (0.48–1.13) | 0.160 |
| DPB1*0401-DPA1*0202 | 3.0 | 2.0 | 2.7 | 1.02 (0.68–1.52) | 0.930 | 1.51 (0.85–2.66) | 0.157 |
| DPB1*0201-DPA1*0103 | 12.4 | 9.3 | 6.9 | 1.76 (1.39–2.25) | <0.001 | 1.38 (1.04–1.83) | 0.024 |
| DPB1*0201-DPA1*0202 | 6.7 | 5.0 | 4.8 | 1.30 (0.97–1.74) | 0.078 | 1.37 (0.94–1.99) | 0.098 |
| DPB1*0202-DPA1*0202 | 7.0 | 4.7 | 9.3 | 0.67 (0.52–0.85) | 0.001 | 1.52 (1.04–2.22) | 0.030 |
Abbreviation: OR, odds ratio; CI, confidence interval; † Cases including the group of anti-F positive and anti-F negative; * The p values, OR, and 95% CI were calculated by Person Chi-Square test; Bold represent the p values were considered statistically significant.