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The expression of TLR4 mRNA in the neonatal rat brain. At all ages detected, icv. injection of LPS induced dramatic increase in TLR4 mRNA expression (*** p < 0.001), compared with that in the peripheral LPS, central NS and peripheral NS injection groups. No significant difference was found in the TLR4 mRNA expression in the neonatal rat brains between ip. injections of LPS and NS.
