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. 2014 Jun 5;15(6):10101–10115. doi: 10.3390/ijms150610101

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© 2014 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

PMC Copyright notice

The protein levels of myeloid differentiation factor 88 (MyD88), nuclear transcription factor kappa-B (NF-κB) p50 and tumor necrosis factor alpha (TNFα) 6, 12 and 24 h after icv. or ip. injection of LPS or NS in the P1 rat brain. (A) Representative picture of the immunoblot of MyD88 in the P1 rat brain after icv. or ip. injection of LPS or NS at 3 time points, and the graph of statistical analysis of the immunoblot of MyD88 in the brain in various groups. *** p < 0.001, compared with the central NS injection group; (B) Representative picture of the immunoblot of NF-κB p50 in the P1 rat brain after icv. or ip. injection of LPS or NS at 3 time points, and the graph of statistical analysis of the immunoblot of NF-κB p50 in the brain in various groups. ** p < 0.01 and *** p < 0.001, compared with the central NS injection group; (C) Representative picture of the immunoblot of TNFα in the P1 rat brain after icv. or ip. injection of LPS or NS at 3 time points, and the graph of statistical analysis of the immunoblot of TNFα in the brain in various groups. *** p < 0.001, compared with the central NS injection group.