Figure 2.

MPP⁺-treated co-culture medium of SH-SY5Y and U87 cells can inhibit proliferation of Jurkat cells dissociated with apotosis. (a) The cell number of Jurkat was decreased in MPP⁺-treated co-culture medium compared to control without MPP⁺ (straight line means seeding cell number). The medium derived from the incubation of SH-SY5Y or U87 cells with (or without) the presence of MPP⁺ as background control; ** p < 0.01 compared with Jurkat in co-culture medium without MPP⁺; (b) Caspase3 activity of Jurkat cells in MPP⁺-treated co-culture medium was lower than control without MPP⁺. The medium derived from the incubation of SH-SY5Y or U87 cells with (or without) the presence of MPP⁺ as background control. * p < 0.05 compared with Jurkat in U87 incubation medium without MPP⁺; ** p < 0.01 compared with Jurkat in co-culture medium without MPP⁺.