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Celecoxib enhanced ionizing radiation-induced apoptosis in MB-DPs. (A) MB-DP cells (left) lose their sphere formation ability after treatment with celecoxib plus ionizing radiation (IR). Scale bar = 100 μm; and (B–D) Determination of TUNEL-positive cells, Caspase 3-positive cells and Annexin V-positive cells in MB-DP cells pretreated with various doses of celecoxib with or without following IR exposure (2 Gy). Data shown here are the mean ± SD of three experiments.
