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. 2014 Jun 18;15(6):11013–11029. doi: 10.3390/ijms150611013

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© 2014 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Celecoxib and irradiation may enhance the inhibition on MB tumorigenesis and recipient survival in orthotopic MB-DP-transplanted immunocompromised mice. (A) Representative bioluminescence images (BLI) of immunocompromised mice transplanted with MB-DP cells or MB-DN cells with firefly luciferase labeling at the indicated time points after cell inoculation; (B) Quantification of tumor volume in recipients of MB-DN cells or MB-DP cells treated with celecoxib, IR, or the combination of celecoxib and IR; and (C) The cumulative survival of MB-DP cells-xenotransplanted recipients receiving celecoxib, IR or the combination of celecoxib and IR. p < 0.05 vs. MB-DPs.