Table 1.
Characteristics of low- and high-risk clinical groups with anal cancer
| Low Riska (n=62) | High Risk (n=59) | Total (n=121) | p-valueb | ||||
|---|---|---|---|---|---|---|---|
| n | % | n | % | n | % | ||
| Median Age (min-max) | 54 (37-78) | 53 (25-79) | 54 (25-79) | ||||
| Mean age (SD) | 55.5 (9.7) | 54.4 (10.4) | 55.0 (10.0) | 0.54 | |||
| Gender | |||||||
| Male | 25 | 40% | 22 | 37% | 47 | 39% | 0.73 |
| Female | 37 | 60% | 37 | 63% | 74 | 61% | |
| Race | |||||||
| White | 52 | 84% | 53 | 90% | 105 | 87% | 0.33 |
| African American/Other | 10 | 16% | 6 | 10% | 16 | 13% | |
| KPS | |||||||
| 60-70 | 3 | 5% | 3 | 5% | 6 | 5% | 1.00 |
| 80-100 | 59 | 95% | 56 | 95% | 115 | 95% | |
| Mean tumor size (SD) | 3.5 (0.9) | 5.6 (2.3) | 4.5 (2.0) | --c | |||
| T-Stage | |||||||
| T2 | 60 | 97% | 24 | 41% | 84 | 69% | --c |
| T3/T4 | 2 | 3% | 35 | 59% | 37 | 31% | |
| N-Stage | |||||||
| N0 | 62 | 100% | 23 | 39% | 85 | 70% | --c |
| N1 | 0 | 0% | 11 | 19% | 11 | 9% | |
| N2 | 0 | 0% | 14 | 24% | 14 | 12% | |
| N3 | 0 | 0% | 5 | 8% | 5 | 4% | |
| Nx | 0 | 0% | 6 | 10% | 6 | 5% | |
Abbreviations: min, minimum; max, maximum; SD, standard deviation, KPS, Karnofsky Performance Status
a
Low-risk = tumors ≤5 cm and N0; High-risk= tumors >5 cm and/or N+
b
Statistical differences in patient characteristics between the two groups were determined by Chi-square test, Fisher's exact test, or t-test.
c
Testing not applicable for tumor size and N-stage, as those variables define the risk groups. Similarly for T-stage, which is highly associated with tumor size by AJCC 1997 version definition.