Table 5.
Rates of reactivation after inhibition with soman.
| Enzyme | kreactivation (1/h) | % Reactivated | Fold increase |
|---|---|---|---|
| WT | 0.001 ± 0.004 | <4% after 5.5 h | – |
| A107H | 0.7 ± 0.1 | 106 ± 8 | 700 |
| A107H/A190Ca | 1.8 ± 0.2 | 44 ± 5 | 1800 |
| A107H/A190Cb | 4 ± 1 | 43 ± 6 | 4000 |
| A107H/A190C/A400Ma | 0.7 ± 0.2 | 20 ± 2 | 700 |
| A107H/A190C/A400Mb | 1.2 ± 0.5 | 17 ± 2 | 1200 |
Without heating prior to inhibition.
With 2 h of heating at 37°C prior to reactivation at 37°C.