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Rates of reactivation of hCE1 after inhibition with paraoxon.
| Enzyme | pH | kreactivation (1/h) | % Reactivated |
|---|---|---|---|
| hCE1 WT | 7.0 | 0.078 ± 0.006 | 92 ± 3 |
| 7.6 | 0.102 ± 0.006 | 98 ± 3 | |
| hCE1 G143H | 7.0 | 0.025 ± 0.008 | 45 ± 8 |
| 7.6 | 0.03 ± 0.03 | 15 ± 2 | |
| hCE1 G143H/A222C | 7.0 | 0.007 ± 0.003 | 120 ± 60 |
| 7.6 | 0.009 ± 0.007 | 11 ± 8 |
