Table 1.
Correlation between NED and clinicopathological parameters.
| Property | NED | P value | |
|---|---|---|---|
| Negative | Positive total (SG1, SG2, and SG3) |
||
| Age | |||
| <65 | 59 | 38 (14, 5, 19) | 0.532 |
| ≥65 | 41 | 33 (15, 6, 12) | |
| Gender | |||
| Male | 65 | 33 (10, 6, 17) | 0.019 |
| Female | 35 | 38 (19, 5, 14) | |
| Tumor location | |||
| Colon | 70 | 45 (14, 8, 23) | 0.410 |
| Rectum | 30 | 26 (15, 3, 8) | |
| Lymphatic invasion | |||
| Yes | 24 | 19 (9, 1, 9) | 0.722 |
| No | 76 | 52 (20, 10, 22) | |
| Lymph nodes discovered | |||
| ≥12 | 70 | 53 (22, 8, 23) | 0.605 |
| <12 | 30 | 18 (7, 3, 8) | |
| TNM stage | |||
| I | 5 | 3 (1, 1, 1) | 0.135 |
| II | 28 | 14 (5, 3, 6) | |
| III | 47 | 46 (18, 6, 21) | |
| IV | 20 | 8 (5, 1, 3) | |
| Chemotherapy | |||
| Yes | 54 | 28 (11, 4, 13) | 0.065 |
| No | 46 | 43 (18, 7, 18) | |
SG: subgroup; SG 1: 1–10 positive cells/HPF; SG 2: 11–20 cells/HPF; SG 3: >20 cells/HPF; NED: neuroendocrine differentiation; TNM: tumor, node, metastasis.